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Pathophysiology paper related to sepsis, septic shock, and SIRS. Paying careful

Pathophysiology paper related to sepsis, septic shock, and SIRS. Paying careful attention to the instructions and rubrics, and utilizing the provided resources and additional resources for a total of 5, including the video and SIRS detail below.

SIRS criteria, originally defined by Bone et al (1992). It continues to be cited in the literature today but this is the original source. Here are the four criteria:

Temperature ˃38C or ˂36C

Heart rate ˃90 beats per minute

Respiratory Rate ˃20/ min

WBC count ˃12,000/cu mm or ˂4,000/cu mm

Bone, R. C., Balk, R. A., Cerra, F. B., Dellinger, R. P., Fein, A. M., Knaus, W. A., Shein, R. M. & Sibbald, W. J. (1992). Definitions for
sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest, 101, 1644-1655. doi:10.1378/
chest.101.6.1644

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